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Herpes is shockingly common. Up to a fifth of all Americans have HSV-2, or genital herpes, although 87 percent of HSV-2 cases are never clinically diagnosed, thanks to the fact that many people infected by the virus never develop symptoms. They can also cause flulike symptoms the first time they appear, and for about a third of people with symptomsreoccur several times a year. But even best-case asymptomatic herpes carriers can infect others, who may suffer more from the virus.